This paper arises from a comparison of the organisations that are considered Defence Colleges, according to the selection made by the Association of Ibero-American Defence Colleges, in the countries that are part of the South American South Pacific region: Chile, Colombia, Ecuador and Peru. In this sense, the comparison is based on four dimensions: having an academic and indexed journal, having training and education processes available to civilians, having different levels of training and education, and having a Strategic Studies Centre within its structure. These dimensions will allow us to have a conception of the role played by those Defence Colleges in the field of knowledge generation and dissemination, while at the same time establishing similarities and differences in terms of content, programmes and academic processes. The conclusion is that there is a tendency towards similarity in the programmes offered by the Defence Colleges, with only one case of exception, which results in a sort of perception of homogenisation of the threats and processes of Defence within the respective countries studied.